Abruquinone derivatives and their uses

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514453, 514456, 4241951, A61K 3135, A61K 3578

Patent

active

055631673

ABSTRACT:
Disclosed are methods of isolation and purification of active constituents from Hsian-ssu-tsu (Abrus precatorius L.), and the therapeutical applications of the purified compounds. From the cloroform fraction of the methanolic extract of the roots of Abrus precatorius L., Abruquinones A, B, D, E, F, which are shown as Compounds I through V, respectively, as follows: ##STR1## were isolated and identified Pharmacological evaluations showed that these compounds possess an activity to inhibit platelet aggregation, as well as antiinflammatory, and antiallergic activities.

REFERENCES:
Chemical Abstracts 91: 157554k, 1979.

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