ABCA1 elevating compounds

Details ABCA1 elevating compounds ABCA1 elevating compounds

2006-12-07

2009-08-25

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C564S091000, C514S604000

Reexamination Certificate

active

07579504

ABSTRACT:
The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.

REFERENCES:
patent: WO03/053912 (2003-07-01), None
patent: WO2006/048330 (2006-05-01), None
A. Moreno, et al., “Synthesis and Evaluation of New Arylsulphonamidomethylcyclohexyl Derivatives as Human Neuropeptide Y Y5 Receptor Antagonists for the Treatment of Obesity”;European Journal of Medicinal Chemistry; vol. 39, No. 1, Jan. 2004 pp. 49-58.

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