A84575 antibiotics

Details A84575 antibiotics A84575 antibiotics

1991-06-27

1994-02-15

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 713, 435822, C12R 101, C12N 120, C12P 2104

Patent

active

052866483

ABSTRACT:
Newly discovered lipoglycopeptide antibiotic A84575 complex, comprising factors A, B, C, D, E, F, G, and H, is produced by submerged aerobic fermentation of a culture selected from Streptosporangeum carneum NRRL 18437, Streptosporangeum carneum NRRL 18505 or an A84575-producing mutant thereof. The antibiotics are active against Gram-positive bacteria.

REFERENCES:
patent: 4461723 (1984-07-01), Hershberger et al.
patent: 4558036 (1985-12-01), Merkel et al.
patent: 4782042 (1988-11-01), Selva et al.
Waltho et al., "Structure Elucidation of the Glycopeptide Antibiotic Complex A40926," J. Chem. Soc. Perkin Trans I, 2103-2107 (1987).
S. B. Christenson et al., "Parvodicin, A Novel Glycopeptide from a New Species Actinomadura parvosata: Discovery, Taxonomy, Activity and Structure Elucidation," J. Antibiotics 60(7), 970-990 (1987).
F. P. Mertz et al., "Streptosporangeum carneum sp. nov. Isolated from Soil," Intern. J. Systematic Bacteriol. 40(3), 247-253 (1990).
SmithKline Beckman Corp., "New Macrocyclic Glycopeptide Antibiotic Complex AAJ-271-Useful Therapeutically and as Animal Feed Additive, and New Actinomadura Parvosata Species," Derwent Abstract 88-030461/05 of EP-255-256-A.

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