A82846 antibiotics

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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4352522, 435872, 514 10, C12P 1960, C12N 120

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active

053127382

ABSTRACT:
New glycopeptide antibiotic A82846, comprising A82846A, A82846B and A82846C, is produced by Nocardia orientalis strains NRRL 18098, NRRL 18099 and NRRL 18100. The A82846 antibiotics have activity against Gram-positive bacteria comparable to that of vancomycin.

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patent: 4548924 (1985-10-01), Michel
patent: 4548925 (1985-10-01), Higgins et al.
patent: 4558008 (1985-10-01), Boeck et al.
C. M. Harris et al., "The Role of the Chlorine Substituents in the Antibiotic Vancomycin: Preparation and Characterization of Mono- and Didechloro-vancomycin," J. Amer. Chem. Soc. 107, 6652-6658 (1985).
Harris et al., "Structure of the Glycopeptide Antibiotic Vancomycin. Evidence for an Asparagine Residue in the Peptide," J. Amer. Chem. Soc. 104, 4293-4295 (1982).
G. F. Gauze et al., "Eremomycin, A Novel Cyclic Glycopeptide Antibiotic," Antibiot. Med. Biotechnol. 32 (8), 571-576 (1987). Abstract only.

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