Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1990-05-09
1994-05-17
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
4352522, 435872, 514 10, C12P 1960, C12N 120
Patent
active
053127382
ABSTRACT:
New glycopeptide antibiotic A82846, comprising A82846A, A82846B and A82846C, is produced by Nocardia orientalis strains NRRL 18098, NRRL 18099 and NRRL 18100. The A82846 antibiotics have activity against Gram-positive bacteria comparable to that of vancomycin.
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C. M. Harris et al., "The Role of the Chlorine Substituents in the Antibiotic Vancomycin: Preparation and Characterization of Mono- and Didechloro-vancomycin," J. Amer. Chem. Soc. 107, 6652-6658 (1985).
Harris et al., "Structure of the Glycopeptide Antibiotic Vancomycin. Evidence for an Asparagine Residue in the Peptide," J. Amer. Chem. Soc. 104, 4293-4295 (1982).
G. F. Gauze et al., "Eremomycin, A Novel Cyclic Glycopeptide Antibiotic," Antibiot. Med. Biotechnol. 32 (8), 571-576 (1987). Abstract only.
Hamill Robert L.
Mabe James A.
Mahoney David F.
Nakatsukasa Walter M.
Yao Raymond C.
Eli Lilly and Company
Harrison Nancy J.
Marx Irene
McClain Janet T.
Whitaker Leroy
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