A60-antigen from Mycobacteria and use thereof as tuberculin and

Details A60-antigen from Mycobacteria and use thereof as tuberculin and A60-antigen from Mycobacteria and use thereof as tuberculin and

1988-04-29

1990-10-23

Spiegel, Jack

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 4, 435863, 435864, 436501, 436811, 436815, 530806, 530820, 530825, 424 87, 424 92, G01N 3353, G01N 35566, C12Q 100, A61K 3940

Patent

active

049651927

ABSTRACT:
An interspecific antigen of Mycobacteria consists essentially of a mixture in substantially immunochemically pure form of a protein having a molecular weight of at least about 4.times.10.sup.6 Daltons and polysaccharide having a molecular weight of at least about 1.times.10.sup.6 Daltons, and has when subjected to cross-electrophoresis an immunoelectrophoretic precipitation pattern corresponding to A60-antigen of Mycobacteria bovis strain BCG. This antigen is effective for detecting the prior exposure of a subject to Mycobacterial infections by a cutaneous test.

REFERENCES:
patent: 4410660 (1983-10-01), Straus
patent: 4591552 (1986-05-01), Neurath
patent: 4777130 (1988-10-01), Maes

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