A52688 Antibiotics and process for their production

Details A52688 Antibiotics and process for their production A52688 Antibiotics and process for their production

1983-12-16

1985-08-27

Torrence, Dolph H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

260464, 260465D, 435128, A01N 3734, C07C11902, C12P 1300

Patent

active

045377774

ABSTRACT:
New A52688 factors A, C, D, E, F, G, H, J and K which have the common general formula: ##STR1## are antibacterial and antineoplastic agents. Methods of preparing the antibiotics by culturing a strain of Mycoleptodiscus terrestris are provided.

REFERENCES:
"J. Berdy, CRC Handbook of Antibiotic Compounds", vol. VI, CRC Press, Boca Raton, Fla., pp. 273-274.
A. Takatsuki et al., "New Antiviral Antibiotics; Xanthocillin X Mono- and Dimethylether, and Methoxyxanthocillin X Dimethylether, I. Isolation and Characterization", J. Antibiotics, vol. XXI, 671-675, (1968).
T. Korzybski et al., "Antibiotics: Origin, Nature and Properties", vol. II, Pergamon Press, New York, 1967, pp. 1256-1257.
I. T. Harrison, et al., "Antibacterial Activity of N-(B-Styryl)formamides Related to Tuberin", J. Med. Chem. 21 (6), 588-591, (1978).
Centraalbureau Voor Schimmelcultures Baarn, "List of Cultures", 29th ed., 1978, p. 184.

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