A1 adenosine receptor agonists and antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

536 2762, 544267, 544268, 544277, A61K 3152, C07D47308, C07D47306, C07D47334

Patent

active

056681399

ABSTRACT:
Adenosine and xanthine derivatives, and compositions comprising those compounds, are potent selective agonists and antagonists of adenosine receptors. The derivatives and compositions are used to treat conditions, including certain cardiac arrhythmias.

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Jacobson, K.A. et al. (1992) "Adenosine Receptors: Pharmacology, Structure--Activity RElationships, and Therapeutic Potential" Journal of Medicinal Chemistry 35(3):407-422.

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