Aβ-Peptide screening assay

Details Aβ-Peptide screening assay Aβ-Peptide screening assay

2006-09-19

2006-09-19

Falk, Anne-Marie (Department: 1635)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S004000, C435S023000, C435S029000, C435S183000, C435S254110, C435S455000

Reexamination Certificate

active

07109027

ABSTRACT:
The invention relates to a process for the determination of the γ-secretase activity, individual components of the process and the use of the process.The present invention relates to a novel process for the determination of the γ-secretase activity and for the detection of γ-secretase; particular embodiments of the process relate on the one hand to processes for the identification of a γ-secretase or of a cDNA which codes for a γ-secretase and on the other hand to processes for the identification of substances which can inhibit the activity of a γ-secretase. Such substances have particular importance, as they can be used, for example, as pharmaceutical active compounds, e.g. for the treatment of Alzheimer's disease.

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