Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1994-01-27
1997-02-04
Shah, Mukund J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
540460, 560 25, C07D48718, C07D51318, C07D49818
Patent
active
055999263
ABSTRACT:
The subject invention provides chiral receptor molecules having the structure: ##STR1## wherein A has the structure: ##STR2## and R.sub.1 and R.sub.2 are independently the same or different and are H, F, alkyl, aryl, etc.; X is CH.sub.2 or NH; Y is C.dbd.O or SO.sub.2 ; and n is 0 to about 3; which are useful for the purification of enantiomers of amino acid derivatives and other compounds. The subject invention also provides methods of preparing said receptor molecules.
REFERENCES:
patent: 4043979 (1977-08-01), Cram
patent: 4128556 (1978-12-01), Cram
Diederich, F., Complexation of Neutral Molecules by Cyclophan Hosts, Angew. Chem. Int. Ed. Engl., 27:362-386 (1988); Germany.
Ebmeyer, F., and Vogtle, F., Selective Molecular Recognition of Trihydroxybenzenes, Angew. Chem. Int. Ed. Engl., 28:79-81 (1989); Germany.
Fujita, T., and Lehn, J.-M., Synthesis of Dome-Shaped Cyclophane Type Macrotricyclic Anion Receptor Molecules, Tetrahedron Letters, 29 (14):1709-1712 (1988); Great Britain.
Garrett, T. M., et al., Synthesis and Characterization of Macrobicyclic Iron (III) Sequestering Agents, J. Am. Chem. Soc., 113 (13):2965-2977(1991); U.S.A.
Hong, J.-I., et al., Highly Selective Binding of Simple Peptides by a C.sub.3 Macrotricyclic Receptor, J. Am. Chem. Soc., 113 (13):5111-5112 (1991); U.S.A.
Jeong, K.-S., et al., Molecular Recognition. Asymmetric Complexation of Diketopiperazines, J. Am. Chem. Soc., 112:6145-6146 (1990); U.S.A.
Liu, R., et al., Enantioselective Complexation of the Alanine Dipeptide by a C.sub.2 Host Molecule, J. Org. Chem., 55:5184-5186 (1990); U.S.A.
Murakami, Y., et al., Capped Azaparacyclophane, J. Chem. Soc., Chem Commun., 753-755 (1985); Great Britain.
Sanderson, P. E. J., et al., Enantioselective Complexation of Simple Amides by a C.sub.2 Host Molecule, J. Am. Chem. Soc., 111:8314-8315 (1989); U.S.A.
Wambach, L., and V ogtle, F., Tetrahydrofuran-Einschluss und Gast-Selektive Katalyse des H/D-Austauschs in Saurer Losung, Tetrahedron Letters, 26:1483-1486 (1985); Great Britain.
Erickson Shawn D.
Hong Jong-In
Simon Julian A.
Still W. Clark
Yoon Seung S.
Shah Mukund J.
Sripada Pavanaram
The Trustees of Columbia University in the City of New York
White John P.
LandOfFree
A.sub.4 B.sub.6 macrotricyclic enantioselective receptors for am does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A.sub.4 B.sub.6 macrotricyclic enantioselective receptors for am, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A.sub.4 B.sub.6 macrotricyclic enantioselective receptors for am will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-679868