Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-03-25
1995-06-13
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3144
Patent
active
054243220
ABSTRACT:
This invention relates to compositions of substituted pyridinylamino-1H-indoles of the formula ##STR1## wherein Q is N or NR.sub.2 ;
Y is CH
R.sub.1 is hydrogen, loweralkyl, loweralkynyl, loweralkenyl, arylloweralkyl, loweralkoxycarbonylaminoloweralkylcarbonyl, arylloweralkoxycarbonylaminoloweralkylcarbonyl, aminoloweralkylcarbonyl, loweralkoxycarbonyl or acyl;
R.sub.2 is hydrogen or loweralkyl;
R.sub.3 is hydrogen or loweralkyl;
X is hydrogen, loweralkyl, halogen; and
n is 0 or 1 with utility in the treatment of personality disorders as obsessive compulsive disorders.
REFERENCES:
patent: 4970219 (1990-11-01), Effland et al.
patent: 5006537 (1991-04-01), Effland et al.
Goodman et al., Arch. Gen. Psychiatry, vol. 47, Jun., 1990, pp. 577-585.
Parg et al Drug Absorption, Distribution and Elimination pp. 55-56.
Effland Richard C.
Klein Joseph T.
Martin Lawrence L.
Cintins Marianne M.
Hoechst-Roussel Pharmaceuticals Inc.
Maurer Barbara V.
Spivack Phyllis G.
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