A-norandrostane derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260586E, A61K 3112, C07C 4946

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active

041306651

ABSTRACT:
Therapeutically useful A-nor-androsta-3(5),16-dien-2-one derivatives of the general formula: ##STR1## wherein R.sub.1 and R.sub.2 each represent a hydrogen atom or a methyl group, process for their preparation by dehydrating in the 16-17 position a corresponding 17-hydroxy compound, and pharmaceutical compositions for the treatment of dermatological disorders, which comprise, as an active ingredient at least one of the A-nor-steroids as defined by formula I, are disclosed.

REFERENCES:
patent: 4075233 (1978-02-01), Marx et al.
Canceill et al., Compt. Rend. (Acad. Science, Paris), Ser. C. 285, No. 1, pp. 37-40 (1977).
Chemical Abstracts, vol. 71, 3540(c) (1969).

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