A DNA coding for a Flavivirus antigen

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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43525233, 4353201, 536 2372, C12N 510, C12N 121, C12N 1540, C12N 1570

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active

054864739

ABSTRACT:
There is disclosed a DNA which codes for an antigen comprising at least part of an amino acid sequence of the antigen of a flavivirus, which part contains at least one epitope of the flavivirus antigen. The present DNA can be used for producing the antigen easily and safely at low cost by means of recombinant DNA technique. The antigen produced using the present DNA can be used as an effective vaccine and diagnostic for Japanese encephalitis.

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Huynh et al., (1985), "Constructing and Screening cDNA Libraries in .lambda.gt10 and .lambda.gt11", in DNA Cloning ed, Glover (IRL Press, Oxford, UK).
Sumiyoshi et al., (1986), "Sequence of 3000 Nucleotides at the 5' End of Japanese Encephalitis Virus RNA", Gene, vol. 48, pp. 195-201.
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