A-associated H-antigens, monoclonal antibodies specific thereto

Details A-associated H-antigens, monoclonal antibodies specific thereto A-associated H-antigens, monoclonal antibodies specific thereto

1987-01-12

1989-08-15

Griffin, Ronald W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424 88, 514 54, 514832, 530387, 530395, C08B 3700, C07H 100, C07H 300, A61K 3700

Patent

active

048576395

ABSTRACT:
The present invention relates to antigens present in blood group A and blood group AB erythrocytes but absent in blood group B and blood group O erythrocytes. More specifically, the present invention relates to A-associated H-antigens having the following structure: ##STR1## wherein X is a sugar residue and n=0 or a positive integer and wherein R is a primary amino group containing material selected from the group consisting of a polypeptide, a primary amino group containing liquid and a primary amino group containing support; monoclonal antibodies specific thereto and methods for employing the same in blood typing.

REFERENCES:
patent: 4029762 (1977-06-01), Galanos et al.
patent: 4330619 (1982-05-01), Goldstein
patent: 4343797 (1982-08-01), Ecanow
patent: 4609627 (1986-09-01), Goldstein
patent: 4746511 (1988-05-01), Kobatake et al.
patent: 4757003 (1988-07-01), Matsumoto et al.
patent: 4762824 (1988-08-01), Kallenius et al.
Race, R. R. et al., Blood Groups in Man, 6th Ed., pp. 9-13, Blackwell Scientific Publications, Oxford (1975).
Makela, O. et al., J. Immunol., 102:763-771 (1969).
Economidou, J. et al., Vox Sang., 12:321-328 (1967).
Mohn, J. F. et al., Human Blood Groups, pp. 316-325, Eds. Mohn, J. et al., Karger, Basel (1977).
Moreno, C. et al., J. Exp. Med., 134:439-457 (1971).
Kisailus, E. C. et al., J. Exp. Med., 147:830-843 (1978).
Clausen, H. et al., J. Biol. Chem., 261:1380-1387 (1986).
Clausen, H. et al., Proc. Natl. Acad. Sci., USA, 82:1199-1203 (1985).
Hakomori, S., Semin. Hematol., 18:39-62 (1981).
Donald, A. S. R., Eur. J. Biochem., 120:243-249 (1981).
Kannagi, R. et al., J. Biol. Chem., 258:8934-8942 (1983).
Kumazaki, T. et al., Proc. Natl. Acad. Sci. USA, 81:4193-4197 (1984).
Graham, H. A. et al., Human Blood Groups: 5th International Convocation on Immunology, Buffalo, New York (1976), Eds. Mohn, J. F. et al., pp. 257-267, Karger, Basel.
Kannagi, R. et al., FEBS Lett., 175:397-401 (1984).
Clausen, H. et al., Biochem. Biophys. Res. Commun., 124:523-529 (1984).
Clausen, H. et al., J. Biol. Chem., 261:1388-1392 (1986).

Affiliated with

Also associated with

Rating

A-associated H-antigens, monoclonal antibodies specific thereto does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with A-associated H-antigens, monoclonal antibodies specific thereto , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A-associated H-antigens, monoclonal antibodies specific thereto will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-122689