A-associated H-antigens, monoclonal antibodies specific thereto

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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530395, 4351722, 43524026, 43524027, 935103, 536 11, C08B 3700, C07H 100, C07H 300, A61K 3700

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active

049422243

ABSTRACT:
The present invention relates to antigens present in blood group A and blood group AB erythrocytes but absent in blood group B and blood group O erythrocytes. More specifically, the present invention relates to A-associated H-antigens having the following structure: ##STR1## wherein X is a sugar residue and n=O or a positive integer and wherein R is a primary amino group containing material selected from the group consisting of a polypeptide, a primary amino group containing lipid and a primary amino group containing support; monoclonal antibodies specific thereto and methods for employing the same in blood typing.

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