Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1989-04-27
1990-07-17
Griffin, Ronald W.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530395, 4351722, 43524026, 43524027, 935103, 536 11, C08B 3700, C07H 100, C07H 300, A61K 3700
Patent
active
049422243
ABSTRACT:
The present invention relates to antigens present in blood group A and blood group AB erythrocytes but absent in blood group B and blood group O erythrocytes. More specifically, the present invention relates to A-associated H-antigens having the following structure: ##STR1## wherein X is a sugar residue and n=O or a positive integer and wherein R is a primary amino group containing material selected from the group consisting of a polypeptide, a primary amino group containing lipid and a primary amino group containing support; monoclonal antibodies specific thereto and methods for employing the same in blood typing.
REFERENCES:
patent: 4029762 (1977-06-01), Galanos et al.
patent: 4330619 (1982-05-01), Goldstein
patent: 4343797 (1982-08-01), Ecanow
patent: 4609627 (1986-09-01), Goldstein
patent: 4746511 (1988-05-01), Kobatake et al.
patent: 4757003 (1988-07-01), Matsumoto et al.
patent: 4762824 (1988-08-01), Kallenius et al.
Race, R. R. et al., Blood Groups in Man, 6th Ed., pp. 9-13, Blackwell Scientific Publications, Oxford (1975).
Makela, O. et al., J. Immunol., 102:763-771 (1969).
Economidou, J. et al., Vox Sang., 12:321-328 (1967).
Mohn, J. F. et al., Human Blood Groups, pp. 316-325, Eds. Mohn, J. et al., Karger, Basel (1977).
Moreno, C. et al., J. Exp. Med., 134:439-457 (1971).
Kisailus, E. C. et al., J. Exp. Med., 147:830-843 (1978).
Clausen, H. et al., J. Biol. Chem., 261:1380-1387 (1986).
Clausen, H. et al., Proc. Natl. Acad. Sci., U.S.A., 82:1199-1203 (1985).
Hakomori, S., Semin. Hematol., 18:39-62 (1981).
Donald, A. S. R., Eur. J. Biochem., 120:243-249 (1981).
Kanagi, R. et al., J. Biol. Chem., 258: 8934-8942 (1983).
Kumazaki, T. et al., Proc. Natl. Acad. Sci. U.S.A., 81:4193-4197 (1984).
Graham, H. A. et al., Human Blood Groups: 5th International Convocation Immunology, Buffalo, N.Y. (1976), Eds. Mohn, J. F. et al., pp. 257-267, Karger, Bagel.
Kannagi, R. et al., FEBS Lett., 175: 397-401 (1984).
Clausen, H. et al., Biochem. Biophys. Res. Commun., 124:523-529 (1984).
Clausen, H. et al., J. Biol. Chem., 261:1388-1392 (1986).
Griffin Ronald W.
The Biomembrane Institute
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