A-32724 Antibiotics and process for production thereof

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis

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435171, 424115, A61K 3500, C12P 102

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active

043754627

ABSTRACT:
Antibiotic A-32724 complex, comprising microbiologically-active, related factors A, B and C, is produced by submerged, aerobic fermentation of a strain of Chaetomella raphigera Swift NRRL 12331. The A-32724 antibiotics are closely related antibiotics. The individual A-32724 factors are separated by chromatography. In addition to their antibacterial activity, the A-32724 factors inhibit certain enzymes and exhibit antihypertensive properties.

REFERENCES:
Kumagai et al., J. Antibiot. 24(12), 870-875, (1971).
Aoyagi et al., J. Antibiot. 24(12), 860-869, (1971).
Yaginuma et al., J. Antibiot. 33(3), 337-341, (1980).

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