A-30912A Nucleus

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424177, 435 71, C07C10352, H61K 3700, C12P 2104

Patent

active

042934826

ABSTRACT:
A-30912A nucleus, which is prepared by enzymatic deacylation of an antibiotic selected from A-30912 factor A, tetrahydro-A-30912A, and aculeacin A using an enzyme produced by the Actinoplanaceae, preferably by Actinoplanes utahensis. A-30912A nucleus and salts thereof are useful intermediates to prepare new semi-synthetic antifungal agents.

REFERENCES:
patent: 3150059 (1964-09-01), Kleinschmidt et al.
patent: 3978210 (1976-08-01), Mizuno et al.
patent: 4024245 (1977-05-01), Hoehn et al.
patent: 4024246 (1977-05-01), Higgens et al.
patent: 4050989 (1977-09-01), Kuwana et al.
patent: 4173629 (1979-11-01), Dreyfuss et al.
T. Kato et al., J. Antibiotics 29 (12), 1339-1340 (1976).
S. Chihara et al., Agr. Biol. Chem. 37 (11), 2455-2463 (1973).
S. Chihara et al., Ibid. 37 (12), 2709-2717 (1973).
S. Chihara et al., Ibid. 38 (3), 521-529 (1974).
S. Chihara et al., Ibid. 38 (10), 1767-1777 (1974).
T. Suzuki et al., J. Biochem. 56 (4), 335-343 (1964).
J. M. Weber et al., J. Antibiotics 31 (4), 373-374 (1978).
J. Shoji et al., J. Antibiotics 28, 764-769 (1975).
J. Shoji et al., Ibid. 29 (4), 380-389 (1976).
J. Shoji et al., Ibid. (12), 1268-1274 (1976).
J. Shoji et al., Ibid. (12), 1275-1280 (1976).
F. Benz et al., Heln, Chim. Acta. 57, 2459 (1974).
C. Keller-Juslen, et al., Tetrahedron Letters, 4147-4150, 1976, vol. 46.
R. Traber et al., Helv. Chim. Acta. 62, 1252 (1979).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

A-30912A Nucleus does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with A-30912A Nucleus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A-30912A Nucleus will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1206095

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.