A 2B adenosine receptor antagonists

Details A 2B adenosine receptor antagonists A 2B adenosine receptor antagonists

2006-10-24

2006-10-24

Berch, Mark L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

C544S267000, C544S269000, C544S271000, C544S272000, C544S310000, C544S312000

Reexamination Certificate

active

07125993

ABSTRACT:
Disclosed are processes for the synthesis of novel compounds that are A2Badenosine receptor antagonists, having the structure of Formula I or Formula II:by cyclizing a compound of the formula (3):

REFERENCES:
patent: 4452788 (1984-06-01), Bristol et al.
patent: 4558051 (1985-12-01), Sunshine et al.
patent: 4593095 (1986-06-01), Snyder et al.
patent: 4879296 (1989-11-01), Daluge et al.
patent: 5446046 (1995-08-01), Belardinelli et al.
patent: 5532368 (1996-07-01), Kufner-Muhl et al.
patent: 5641784 (1997-06-01), Kufner-Muhl et al.
patent: 5714494 (1998-02-01), Connell et al.
patent: 6060481 (2000-05-01), La Noue et al.
patent: 6117878 (2000-09-01), Linden
patent: 6437124 (2002-08-01), Daluge et al.
patent: 6545002 (2003-04-01), Linden et al.
patent: 0386683 (1990-09-01), None
patent: 956855 (1999-11-01), None
patent: 0956855 (1999-11-01), None
patent: 1084710 (2001-03-01), None
patent: WO 9511681 (1995-05-01), None
patent: WO 9942093 (1999-08-01), None
patent: WO 0009507 (2000-02-01), None
patent: WO 0073307 (2000-12-01), None
Jacobson K A et al: “1,3-Dialkylxanthine derivatives having high potency as antagonists at human A2B adenosine receptors”, Drug Development Research, New York, NY, US, vol. 47, No. 1, 1999, pp. 45-53, XP000942540, abstract; example 10D.
Kuz' Menko II et al, “Reactions of Theophyllines, Chemical Conversions of 8-Aminotheophyllinates” Chemistry of Heterocyclic Compounds (A translation of Khimiya Geterotsiklicheskikh Soedinenii), Plenum Press Co., New york NY, US, vol. 36, No. 8, 2000 pp. 963-970 XP001146936 ISSN: 0009-3122 examples 3K,3L,8.

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