A-21978 Antibiotics and process for their production

Details A-21978 Antibiotics and process for their production A-21978 Antibiotics and process for their production

1980-11-14

1982-05-25

Ore, Dale R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424115, C07C10352

Patent

active

043315941

ABSTRACT:
Antibiotic A-21978 complexes, in particular the A-21978C complex, comprising microbiologically active, related factors, C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosporus NRRL 11379. The individual A-29178C factors are separated and isolated by chromatography. The A-21978 and A-21978C complexes, the A-21978C factors, and pharmaceutically acceptable salts thereof are antibacterial agents and improve growth promotion in poultry.

REFERENCES:
Shoji et al., J. Antibiotics, 1976, vol. 29, pp. 380-389, 1268-1274, 1275-1280.

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