A-21978 Antibiotics and process for their production

Details A-21978 Antibiotics and process for their production A-21978 Antibiotics and process for their production

1978-10-16

1980-06-17

Shapiro, Lionel M.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

435 71, C12D 914

Patent

active

042084032

ABSTRACT:
Antibiotic A-21978 complexes, in particular the A-21978C complex, comprising microbiologically active, related factors C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosporus NRRL 11379. The individual A-29178C factors are separated and isolated by chromatography. The A-21978 and A-21978C complexes; the A-21978C factors; and pharmaceutically acceptable salts thereof are antibacterial agents and improve growth promotion in poultry.

REFERENCES:
Shoji et al., Journal of Antibiotics 29, 380-389, 1268-1274, 1275-1280, (1976).

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