9H-indeno[1,2-b]pyrazine derivatives

Details 9H-indeno[1,2-b]pyrazine derivatives 9H-indeno[1,2-b]pyrazine derivatives

1994-01-31

1995-11-21

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514 80, 544337, 544344, 568327, A61K 31495, C07D49110, C07D49510, C07D24138

Patent

active

054687489

ABSTRACT:
The present invention relates to 9H-indeno[1,2-b]pyrazin-3(4H)-ones and 9H-indeno[1,2-b]pyrazine-2,3(1H,4H)-diones or tautomeric forms thereof which are useful in treating neurological and psychiatric diseases based on the antagonism of the glycine binding site on the NMDA receptor complex.

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patent: 5153195 (1992-10-01), Honore et al.
patent: 5182279 (1993-01-01), Jorgensen et al.
Bergel et al., "Journal of Chemical Society", 1964, University College, (London), pp. 3973-3981.
A. W. Johnson et al., "Journal of Chemical Society", 1960, University College, (London), pp. 3412-3413.

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