9-Thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins a

Details 9-Thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins a 9-Thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins a

1976-11-22

1978-04-18

Demers, Arthur P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260399, 260400, 2602948R, 260401, 2604025, 2604109R, 260413, 424305, 424312, 424314, C07C14714, C11D 128

Patent

active

040851257

ABSTRACT:
This invention relates to 9-thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful for the treatment of skin diseases such as psoriasis, for the prevention of thrombus formation, in stimulating the production of growth hormone in intact animals, and as regulators of the immune response.

REFERENCES:
patent: 3697560 (1972-10-01), Henrick et al.
patent: 3737442 (1973-06-01), Baum
patent: 3970685 (1976-07-01), Untch et al.
patent: 3975427 (1976-08-01), Untch

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