9-substituted 2-(2-n-alkoxyphenyl)-purin-6-ones

Details 9-substituted 2-(2-n-alkoxyphenyl)-purin-6-ones 9-substituted 2-(2-n-alkoxyphenyl)-purin-6-ones

1996-01-16

1999-02-02

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142342, 514262, 544 81, 544118, 544265, 544277, A61K 3152, A61K 31655, C07D47330

Patent

active

058665714

ABSTRACT:
9-Substituted 2-(2-n-alkoxyphenyl)purin-6-ones are prepared by cyclizing correspondingly substituted imidazoles and derivatizing the purines thus obtained. The 9-substituted .sup.2 -(2-n-alkoxyphenyl)purin-6-ones can be employed as active compounds in medicaments, in particular in medicarnents for treatment of inflammations, thromboembolic diseases and cardiovascular diseases.

REFERENCES:
patent: 4451478 (1984-05-01), Simon et al.
patent: 5294612 (1994-03-01), Bacon et al.
patent: 5734053 (1998-03-01), Terrett
L.R. Krepski, et al., Synthesis, pp. 301-303 (1986).
M. Hoey, et al., Biochemical Pharmacology, vol. 40, pp. 193-202 (1980).
F. Logemann, et al., Chemistry and Industry, (13), pp. 541-542 (1980).

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