9-Hydroxyoctahydrobenzo[C]quinolines and intermediates therefor

Details 9-Hydroxyoctahydrobenzo[C]quinolines and intermediates therefor 9-Hydroxyoctahydrobenzo[C]quinolines and intermediates therefor

1980-10-03

1982-07-20

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544 70, 544126, 544230, 544361, 546 15, 42424858, 424250, C07D22112, A61K 3147

Patent

active

043407374

ABSTRACT:
1,9-Dihydroxyoctahydrobenzo[c]quinolines (I), 1-hydroxyhexahydrobenzo-[c]quinoline-9(8H)-ones (II), and 1-hydroxy-tetrahydrobenzo[c]quinolines (IV) useful as CNS agents, especially as analgesics and tranquilizers, as hypotensives, as agents for the treatment of glaucoma and as diuretics; intermediates therefor (III) and derivatives thereof having the formulae ##STR1## wherein R is hydroxy, alkanoyloxy having from one to five carbon atoms and hydroxymethyl;

REFERENCES:
patent: 3499901 (1970-03-01), Hellerbach
patent: 3661914 (1972-05-01), van der Burg
patent: 3822269 (1974-07-01), Jeanmart et al.
patent: 3933893 (1976-01-01), Meyer et al.
patent: 4118559 (1978-10-01), Johnson et al.
patent: 4206225 (1980-06-01), Johnson
patent: 4228169 (1980-10-01), Johnson et al.

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