Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Patent
1980-04-14
1982-11-09
Hines, Robert V.
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
C07C 4752
Patent
active
043586201
ABSTRACT:
Novel 9-aminoalkyl-methanoanthracenes of the formula: ##STR1## wherein A is C.sub.1 -C.sub.4 alkylene or C.sub.3 -C.sub.4 alkenylene and R.sub.1 and R.sub.2 are each hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.4 alkenyl, C.sub.3 -C.sub.4 alkynyl, C.sub.3 -C.sub.6 cycloalkyl(C.sub.1 -C.sub.3)alkyl, ar(C.sub.1 -C.sub.3)alkyl or polyhalo(C.sub.2 -C.sub.4)alkyl or, when taken together with the adjacent nitrogen atom, they may form a 5 to 7-membered nitrogen-containing heterocyclic ring which may contain an additional hetero atom, and their non-toxic salts, which are useful as anti-anxiety, anti-depressant, major tranquilizer, anti-histamine and anti-allergy drugs and can be prepared through a novel key intermediate, i.e. 9-formyl-9,10-dihydro-9,10-methanoanthracene, by various methods.
REFERENCES:
patent: 3399201 (1968-08-01), Schmidt et al.
patent: 3493616 (1970-02-01), Symon
patent: 3579582 (1971-05-01), Symon
Katsube Junki
Sato Hiromi
Sunagawa Makoto
Yamamoto Hisao
Hines Robert V.
Sumitomo Chemical Company Limited
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