9-Deoxy-6,9.alpha.-epoxymethano-5,6-didehydro-PGF.sub.1, amide

Details 9-Deoxy-6,9.alpha.-epoxymethano-5,6-didehydro-PGF.sub.1, amide 9-Deoxy-6,9.alpha.-epoxymethano-5,6-didehydro-PGF.sub.1, amide

1979-08-16

1980-11-18

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

542421, C07D31102

Patent

active

042344930

ABSTRACT:
The present invention relates to novel 9-deoxy-6,9.alpha.epoxymethano-5,6-didehydro-PGF.sub.1, amides, which are useful for inducing a variety of prostacyclin-like pharmacological effects. Accordingly, these compounds are useful pharmacological agents for the same purposes for which prostacyclin is employed.

REFERENCES:
Pace-Asciak et al., Biochem., 10, 3657 (1971).
Pace-Asciak et al., JACS., 98, 2348 (1976).

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