9-Deoxy-5,9.alpha.-epoxy-4,5-cis-17,18-tetradehydro-PGF.sub.1, a

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542421, 2603452, C07D31102

Patent

active

042412056

ABSTRACT:
The present invention relates to novel 9-deoxy-5,9.alpha.-epoxy-4,5-cis-17,18-tetradehydro-PGF, amides, which are useful for inducing a variety of prostacyclin-like pharmacological effects. Accordingly, these compounds are useful pharmacological agents for the same purposes for which prostacyclin is employed.

REFERENCES:
patent: 4124599 (1978-11-01), Kelly
Pace-Asciak et al., Biochem., 10, 3657 (1971).
Pace-Asciak et al., JACS, 98, 2348 (1976).

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