Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1993-03-30
1996-10-29
Lilling, Herbert J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 75, 4352571, 435946, 536 168, C12N 112, C12P 1960
Patent
active
055697577
ABSTRACT:
The present invention is based upon the discovery that a MeOH extract of Anabaena affinis strain VS-1 showed strong cytotoxicity to L1210 murine leukemia cells, and from that extract was isolated the compounds having the following structures, Compounds 1 and 2. These two compounds are believed to be responsible for the cytotoxicity of the marine organism. This is the first report of the isolation and characterization of pyrrolo[3,2-d] pyrimidine derivatives as biosynthetic products. ##STR1##
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Carmichael Wayne W.
Namikoshi Michio
Rinehart Kenneth L.
Lilling Herbert J.
Linek Ernest V.
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