9-Bromo-hexahydro- and octahydro-indolo[2,3 a]quinolizines and u

Details 9-Bromo-hexahydro- and octahydro-indolo[2,3 a]quinolizines and u 9-Bromo-hexahydro- and octahydro-indolo[2,3 a]quinolizines and u

1981-06-02

1984-06-26

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 70, A61K 31475, C07D45900

Patent

active

044566077

ABSTRACT:
New salts of the formula XIIIa and XIIIb are disclosed ##STR1## wherein R.sup.2, R.sup.3 and R.sup.5 are each C.sub.1 to C.sub.6 alkyl and A.sup.- is an anion of a pharmaceutically acceptable acid. Furthermore new compounds of the formula XIVa and XIVb are disclosed: ##STR2## wherein R.sup.2 and R.sup.3 are as defined above. The new salts and compounds are intermediates in the preparation of 10-bromo-vincaminic acid esters. In addition the new salts and compounds have the ability to increase blood circulation and to decrease blood flow resistance in an animal subject while at the same time maintaining a steady pulse rate and blood pressure.

REFERENCES:
patent: 3770729 (1973-11-01), Warnat et al.
patent: 4089856 (1978-05-01), Szantay et al.
patent: 4146643 (1979-05-01), Pfagfli
patent: 4283856 (1981-08-01), Szantay et al.
patent: 4315011 (1982-02-01), Szantay et al.

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