9-aminotetrahydroacridines and related compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546103, 546 14, 546 79, 548241, C07D21910, A61K 3144

Patent

active

052100871

ABSTRACT:
Novel 9-aminotetrahydroacridines and related compounds, intermediates and processes for the preparation thereof, and a method of relieving memory dysfunction are disclosed.

REFERENCES:
patent: 3232945 (1966-02-01), Sigal et al.
patent: 4631286 (1986-12-01), Shutske et al.
patent: 4695573 (1987-09-01), Shutske et al.
G. M. Shutske, et al., Journal of Medicinal Chemistry, vol. 32, pp. 1805 to 1813 (Aug., 1989), entitled "9-Amino-1,2,3,4-tetrahydroacridin-1-ols: Synthesis and Evaluation as Potential Alzheimer's Disease Therapeutics".
A. A. Akhrem, et al., Synthesis, p. 43 (Jan., 1978), entitled "A Convenient One-Step Synthesis of Tetrahydrobenzisoxazoles via 1,3-Cycloaddition of Nitrile Oxides to Cyclohexane-1,3-dione Derivatives".

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