9-aminotetrahydroacridines and related compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546103, 546 14, 548241, C07D21910, A61K 3144

Patent

active

053825942

ABSTRACT:
Novel 9-aminotetrahydroacridines and related compounds, intermediates and processes for the preparation thereof, and a method of relieving memory dysfunction are disclosed.

REFERENCES:
patent: 3232945 (1966-02-01), Sigal
patent: 4631286 (1986-12-01), Shutske
patent: 4695573 (1987-09-01), Shutske
A. A. Akhrem, et al., Synthesis, p. 43 (Jan. 1978), entitled "A Convenient One-Step Synthesis of Tetrahydrobenzisoxazoles via 1,3-Cycloaddition of Nitrile Oxides to Cyclohexane-1,3-dione Derivatives" and published in Russia.
G. M. Shutske, Journal of Heterocyclic Chemistry, vol. 27, pp. 1617 to 1621 (Sep. 1990) entitled "A Novel Synthesis of the Isoxazolo[5,4,3-kl]acridine Ring System"& published in the U.S.
Shutske et al., Journal of Medicinal Chemistry, vol. 32, No. 8, pp. 1805-1813 Aug. 1989.

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