9-amino-pyridazino[4',5':3,4]pyrrolo-[2,1-A]isoquinolines and th

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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A61K 31495

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active

055654525

ABSTRACT:
The invention relates to the use of 9-amino-pyridazino-[4', 5':3,4]pyrrolo[2,1-a]isoquinolines of the formula ##STR1## and the physiologically acceptable salts thereof with acids, bases and complexing agents for preparing agents for treating chronic inflammatory processes, ulcerative colitis and Crohn's disease, and for producing agents having an antiproliferative activity. The definitions of substituents R.sub.1 to R.sub.9 are given in the specification. The invention also relates to new compounds of general formula I which are also defined in the specification and their use as cerebroprotective agents.

REFERENCES:
Loesel et al, Chem. Abst., vol. 105, #172,490 (1986).
Loesel et al, Chem. Abst., vol. 106, #102,310 a (1987).
Loesel et al, Chem. Abst., vol. 109, #204,921 e (1988).

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