Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-05-27
2008-05-27
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S423000, C548S526000
Reexamination Certificate
active
10576201
ABSTRACT:
The invention relates to compounds of formula (I), wherein R1is a group selected from hydrogen, alkyl, aryl, aryalkil, heteroaryl, heteroarylalkyl, alkylcarbonyl, arylcarbonyl, arylalkylcarbonyl, alkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl, heterocycloalkoxycarbonyl, alkylsulfonyl, arylsulfonyl, arylalkylsulfonyl, phosphonic and Si(Ra)2Rb, Y is a group selected from HN—NH and N—R2, R3is a hydrogen atom, an alkyl, cycloalkyl, aryl, arylalkyl group, R4is hydrogen atom or an alkyl group, enantiomers, diastereoisomers and the salts thereof
REFERENCES:
patent: 3634459 (1972-01-01), von Wartburg et al.
patent: 5536847 (1996-07-01), Terada et al.
patent: 5541223 (1996-07-01), Lee et al.
patent: 6566393 (2003-05-01), Lee et al.
patent: 2003/0032625 (2003-02-01), Jensen et al.
patent: WO-90/09788 (1990-09-01), None
patent: WO-97/13776 (1997-04-01), None
Cho et al. J. Med. Chem., 1996, 36, 1383-1395.
Carmichael et al.; “Evaluation of a Tetrazolium-Based Semiautomated Colorimetric Assay: Assessment of Chemosensitivity Testing”; Cancer Research, vol. 47, pp. 936-942, Feb. 15, 1987.
Cho et al.; “Antitumor Agents. 163. Three-Dimensional Quantitative Structure-Activity Relationship Study of 4′-O-Demethylepipodophyllotoxin Analogs Using the Modified CoMFA/q2-GRS Approach”; J. Med. Chem. vol. 39, pp. 1383-1395, (1996).
Benard Pierre
Dauzonne Daniel
Hickman John
Kraus-Berthier Laurence
Monneret Claude
Centre National de la Recherche Scientifique "CNRS"
Foley & Lardner LLP
Havlin Robert
Les Laboratoires Servier
Saeed Kamal A.
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