9.alpha.,5-Nitrilo-9-deoxy-PGF.sub.1 compounds

Details 9.alpha.,5-Nitrilo-9-deoxy-PGF.sub.1 compounds 9.alpha.,5-Nitrilo-9-deoxy-PGF.sub.1 compounds

1978-04-05

1979-05-01

Demers, Arthur P.

Harness for working animal

546183, 546112, 424256, 542421, 542422, 542416, 542427, 542429, C07D22104

Patent

active

041525140

ABSTRACT:
This invention relates to certain structural and pharmacological analogs of prostacyclin (PGI.sub.2) wherein a nitrogen atom is substituted for the 6,9.alpha.-epoxy-oxygen of prostacyclin. These novel nitrogen-containing prostacyclin-type compounds are useful for the pharmacological purposes for which prostacyclin is used, e.g., as antithrombotic agents, antihypertensive agents, antiasthma agents, nasal decongestants, or regulators of fertility and procreation.

REFERENCES:
patent: 3931289 (1976-01-01), Bundy
patent: 3983157 (1976-09-01), Bundy
patent: 3983178 (1976-09-01), Bundy

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