9-Alkoxy-5-methyl-6,7-benzomorphans

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602472B, 2602475GP, 260DIG13, 424248, 424267, C07D 3900

Patent

active

039563367

ABSTRACT:
N-Substituted-9-alkoxy-5-methyl-6,7-benzomorphans have been found to possess potent narcotic agonist and/or antagonist activity. In particular, the compound 2-cyclopropylmethyl-2'-hydroxy-9.alpha.-methoxy-5-methyl-6,7-benzomorphan has been found to possess potent narcotic agonist and antagonist activity. These compounds are prepared by total synthesis and are not derived from opium alkaloids.

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May, et al., J. Org. Chem. 26: 1954 (1961).
May, et al., J. Org. Chem. 26: 4536 (1961).
May, et al., J. Med. Chem. 8: 235 (1965).

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