9-(3-O-Acyl-.beta.-D-arabinofuranosyl)adenine compounds, 9-(2,3-

Details 9-(3-O-Acyl-.beta.-D-arabinofuranosyl)adenine compounds, 9-(2,3- 9-(3-O-Acyl-.beta.-D-arabinofuranosyl)adenine compounds, 9-(2,3-

1976-05-17

1977-10-25

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 24, C07H 1918, A61K 3152

Patent

active

040557170

ABSTRACT:
9-(3-O-Acyl-.beta.-D-arabinofuranosyl)adenine compounds, 9-(2,3-di-O-acyl-.beta.-D-arabinofuranosyl)adenine compounds, and their production by reacting in each case the corresponding 5-silyl ether derivative with a tetraalkylammonium fluoride. The compounds are useful as antiviral agents. The compounds are water-soluble and lipophilic, thereby being adaptable to a wide variety of pharmaceutical formulations.

REFERENCES:
patent: 3309358 (1967-03-01), Hanze
patent: 3354160 (1967-11-01), Duschinsky et al.
patent: 3457253 (1969-07-01), Wechter
patent: 3651045 (1972-03-01), Haskell et al.

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