Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1976-08-16
1979-05-15
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
546332, C07D25308
Patent
active
041549295
ABSTRACT:
The discovery of 9-(2-pyridyl)-acenaphtho[ 1,2-e]-as-triazine and its sulfonated form, having particular advantages when used as both a chelator and indicator of ferrous ions in organic or aqueous mediums; a process for the synthesis of those compounds in which hydrazine is used as both a reactant and as a solvent in production of intermediate compounds, eliminating the need of ethanol and the disadvantageous ether-extraction step; the use of N,N-dimethylformamide as a reaction solvent in the production of triazines; the use of the new triazine compounds to measure iron, transferrin, and UIBC/TIBC in biological systems; the use of dimethylsulfoxide and certain processes to eliminate interferences commonly encountered in these assays; and the use of the triazine compounds to measure both total and/or reduced iron in a variety of matrices.
REFERENCES:
patent: 4008232 (1977-02-01), Lacefield
patent: 4033752 (1977-07-01), Hashimoto et al.
Denney Jerry W.
Outcalt Mark C.
American Monitor Corporation
Ford John M.
Spray Robert A.
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