9-(2-O-Acyl-.beta.-D-arabinofuranosyl)-adenine compounds and met

Details 9-(2-O-Acyl-.beta.-D-arabinofuranosyl)-adenine compounds and met 9-(2-O-Acyl-.beta.-D-arabinofuranosyl)-adenine compounds and met

1976-05-17

1977-10-25

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

195 28N, 424181, 536 24, A61K 3152, C07H 1918

Patent

active

040557189

ABSTRACT:
9-(2-O-Acyl-.beta.-D-arabinofuranosyl)adenine compounds and their production by enzymatic removal of the 3-O-acyl and 5-O-acyl groups of a 9-(2,3-di-O-acyl-.beta.-D-arabinofuranosyl)adenine compound or a 9-(2,3,5-tri-O-acyl-.beta.-D-arabinofuranosyl)adenine compound. The monoester compounds are useful as antiviral agents. The compounds are watersoluble and lipophilic, thereby being adaptable to a wide variety of pharmaceutical formulations.

REFERENCES:
patent: 3309358 (1967-03-01), Hanze

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