Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-05-11
1988-11-01
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514261, 544276, 544277, C07D47318, A61K 3152
Patent
active
047820624
ABSTRACT:
9-[2-(Hydroxymethyl)cycloalkylmethyl]guanines which are herpes simplex viral thymidine kinase inhibitors, their acyl derivatives, their phosphate derivatives and their pharmaceutically-acceptable salts; pharmaceutical formulations containing these compounds; the treatment of DNA viral, particularly herpes viral, infections with these compounds; methods of preparing these compounds; and novel intermediates useful in their preparation.
REFERENCES:
patent: 4617304 (1986-10-01), Ashton et al.
Ashton Wallace T.
Karkas John D.
Tolman Richard L.
Merck & Co. , Inc.
Parr Richard S.
Pfeiffer Hesna J.
Rizzo Nicholas S.
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