9,11-Dihalo-PG.sub.2 compounds

Details 9,11-Dihalo-PG.sub.2 compounds 9,11-Dihalo-PG.sub.2 compounds

1977-06-17

1979-02-20

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260239PF, 2603264, 260556R, 260556AR, 260408, 260557R, 260557D, 260559B, 260559R, 429365, 429317, 544391, 5445516, 562444, 562465, 546226, 546314, 560557, 568838, 568807, 568645, 568669, 542429, 542408, 560503, C07C17700

Patent

active

041408632

ABSTRACT:
The present invention relates to certain 9,11-dideoxy-PGF-type compounds wherein the C-9 and C-11 carbon atoms are substituted by halogen. In particular, 9,11-chloro-, 9,11-bromo-, and 9,11-iodo-9,11-dideoxy-PGF compounds are disclosed.
These compounds are particularly useful for numerous pharmacological purposes, based on their ability to stimulate mammalian smooth muscle tissue.

REFERENCES:
patent: 3997587 (1976-12-01), Muchowski et al.

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