Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-09-19
1976-06-08
Gerstl, Robert
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260209R, 2603433R, 2603457, 2603462R, 260473A, 260504, 260514D, 260520B, 260617R, 424305, 424308, 424317, C07C 6138, C07C 6974
Patent
active
039623122
ABSTRACT:
Prostaglandin compounds of the formula: ##SPC1##
Wherein A represents a grouping of formula II, III or IV indicated below and (i)R.sub.1 represents an unsubstituted n-butyl, n-pentyl, n-hexyl or n-heptyl radical, or such a radical carrying one, two or three alkyl substituents of 1 to 4 carbon atoms, or R.sub.1 represents a methyl, ethyl, propyl or butyl radical carrying a phenyl, cyclohexyl or cyclopentyl substituent, R.sub.2 represents a hydrogen atom or an alkyl radical of 1 to 4 carbon atoms, and R.sub.3 represents a hydrogen atom, or (ii) R.sub.1 represents n-butyl, or n-butyl or n-pentyl carrying one, two or three alkyl substituents of 1 to 4 carbon atoms, or R.sub.1 represents a methyl, ethyl, propyl or butyl radical carrying a phenyl, cyclohexyl or cyclopentyl substituent, R.sub.2 represents a hydrogen atom or an alkyl radical of 1 to 4 carbon atoms, and R.sub.3 represents an alkyl radical of 1 to 4 carbon atoms are disclosed. These compounds exhibit characteristic prostaglandin-like activity.
REFERENCES:
patent: 3843713 (1974-10-01), Finch et al.
Kirton et al., Biochem. and Biophys. Research Comm. 47, 903 (1972).
Hamberg et al., J. Biol. Chem. 246, 1073, (1971).
Hayashi Masaki
Ito Hiroyuki
Ohyama Isao
Tanouchi Tadao
Chow Frank S.
Gerstl Robert
Graddis Albert H.
Ono Pharmaceutical Company
LandOfFree
9,11,15-Trihydroxy prost-5-enoic acid analogues does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 9,11,15-Trihydroxy prost-5-enoic acid analogues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 9,11,15-Trihydroxy prost-5-enoic acid analogues will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1099536