8a-aza-8a-homoerythromycin lactams

Details 8a-aza-8a-homoerythromycin lactams 8a-aza-8a-homoerythromycin lactams

1992-03-27

1993-04-13

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

514183, C07D26700, A61K 31395

Patent

active

052024342

ABSTRACT:
Lactams of the general structural formula: ##STR1## wherein R is hydrogen or C.sub.1-10 alkyl. These compounds are macrolides useful as antibiotics and as intermediates for the synthesis of other macrolide antibiotics.

REFERENCES:
Paur, et al., SCH 23831, a novel macrolide from Micromonospora rosaria, Tetrahedron Letters, No. 30, pp. 2767-2770 (Jul. 1979).

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