Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-07-24
2007-07-24
Rao, Deepak (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S279000
Reexamination Certificate
active
11225218
ABSTRACT:
The invention relates to substituted-pyrimidone derivatives represented by formula (I) or a salt thereof:wherein X, Y, R1, R2, R3, R4, R5, n, p and q are as defined herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer's disease.
REFERENCES:
patent: 1184383 (2002-03-01), None
patent: WO 02/18386 (2002-03-01), None
Ulrich, Crystallization—4. Crystal Characteristics, Kirk-Othmer Encylopedia of Chemical Technology, Aug. 2002.
Vippagunta et al., Crystalline Solids, Advanced Drug Delivery Reviews, 48, pp. 3-26, 2001.
West, Solid Solutions, Solid State Chemistry and its applications, pp. 358 & 365, 1988.
Julien et al., PubMed Abstract (Prog Nucleic Acid Res Mol Biol. 61:1-23), 1998.
Liu et al., PubMed Abstract (J Neurochem 87(6):1333-44), Dec. 2003.
Damasio, Alzheimer's Disease and Related Dementias, Cecil Textbook of Medicine, 20th Edition, vol. 2, pp. 1992-1996, 1996.
Layzer, Degenerative Diseases of the Nervous System, Cecil Textbook of Medicine, 20th Edition, vol. 2, pp. 2050-2057, 1996.
Simone, Oncology: Introduction, Cecil Textbook of Medicine, 20th Edition, vol. 1, pp. 1004-1010, 1996.
Lochead Alistair
Saady Mourad
Slowinski Franck
Yaiche Philippe
Gupta Balaram
Mitsubishi Pharma Corporation
Rao Deepak
Sanofi-Aventis
LandOfFree
8-Substituted-6,7,8,9-tetrahydropyrimido [1,2-a]... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 8-Substituted-6,7,8,9-tetrahydropyrimido [1,2-a]..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 8-Substituted-6,7,8,9-tetrahydropyrimido [1,2-a]... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3738827