8-Substituted-2-(4-pyridinyl)-9H-purin-6-amines and their cardio

Details 8-Substituted-2-(4-pyridinyl)-9H-purin-6-amines and their cardio 8-Substituted-2-(4-pyridinyl)-9H-purin-6-amines and their cardio

1983-01-17

1984-09-25

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544277, 544276, A61K 3152, C07D47334

Patent

active

044735715

ABSTRACT:
8-Q-2-PY-9H-purin-6-amines (II), salts thereof, their preparation and cardiotonic use are shown, where PY is 4-pyridinyl or 4-pyridinyl having one or two lower-alkyl substituents, and Q is methyl, ethyl, 1-methylethyl, 1,1-dimethylethyl, methylthio and ethylthio. Also shown as intermediates for the compounds where Q is methylthio or ethylthio are the corresponding 6-amino-2-PY-9H-purin-8-thiols.

REFERENCES:
patent: 3041340 (1962-06-01), Bullock et al.
Taylor et al., [J. Am. Chem. Soc. 81, 2442-8, (1959)].
Baddiley et al., [J. Chem. Soc. 1943, pp. 386-387].

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