8-(oxo-substituted cycloalkyl)xanthines

Details 8-(oxo-substituted cycloalkyl)xanthines 8-(oxo-substituted cycloalkyl)xanthines

1988-09-16

1992-12-29

Rivers, Diana G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

544271, C07D47304, C07D47306, A61K 3152

Patent

active

051752905

ABSTRACT:
1,3-Substituted-8-(oxo-substituted cycloalkyl)xanthines and pharmaceutically acceptable salts of such compounds are disclosed. Preferred compounds include the cis and trans isomers of 1,3-dipropyl-8-(3-hydroxycyclopentyl)xanthine and the cis and trans isomers of 1,3-dipropyl-8-(4-hydroxycyclohexyl)xanthine. The compounds are potent and selective bronchodilators and/or cardiotonic agents.

REFERENCES:
patent: 4612315 (1986-09-01), Jacobson et al.
patent: 4696932 (1987-09-01), Jacobson et al.
patent: 4755517 (1988-07-01), Bruns et al.
patent: 4769377 (1988-09-01), Snyder et al.
patent: 4772607 (1988-09-01), Badger et al.
patent: 4783530 (1988-11-01), Rzeszotarski et al.
Erdnt, et al., Chemical Abstracts, vol. 86: 72,580n (1977).
Shamim, et al., Chemical Abstracts, vol. 108: 94,512s (Mar. 1988).
Shamim, et al, J. Med. Chem., vol. 31, No. 3, pp. 613-617 (Mar. 1988).

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