8-(oxo-substituted cycloalkyl)xanthines

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen bonded directly to ring carbon of the purine ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

544271, C07D47304, C07D47306, A61K 3152

Patent

active

051752905

ABSTRACT:
1,3-Substituted-8-(oxo-substituted cycloalkyl)xanthines and pharmaceutically acceptable salts of such compounds are disclosed. Preferred compounds include the cis and trans isomers of 1,3-dipropyl-8-(3-hydroxycyclopentyl)xanthine and the cis and trans isomers of 1,3-dipropyl-8-(4-hydroxycyclohexyl)xanthine. The compounds are potent and selective bronchodilators and/or cardiotonic agents.

REFERENCES:
patent: 4612315 (1986-09-01), Jacobson et al.
patent: 4696932 (1987-09-01), Jacobson et al.
patent: 4755517 (1988-07-01), Bruns et al.
patent: 4769377 (1988-09-01), Snyder et al.
patent: 4772607 (1988-09-01), Badger et al.
patent: 4783530 (1988-11-01), Rzeszotarski et al.
Erdnt, et al., Chemical Abstracts, vol. 86: 72,580n (1977).
Shamim, et al., Chemical Abstracts, vol. 108: 94,512s (Mar. 1988).
Shamim, et al, J. Med. Chem., vol. 31, No. 3, pp. 613-617 (Mar. 1988).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

8-(oxo-substituted cycloalkyl)xanthines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 8-(oxo-substituted cycloalkyl)xanthines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 8-(oxo-substituted cycloalkyl)xanthines will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1888460

All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.