8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives

Details 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives

1976-06-08

1978-07-25

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, C07D27908

Patent

active

041030869

ABSTRACT:
Novel bicyclic .beta.-lactams and intermediates useful in their preparation are disclosed. In particular, 7.beta.-acyl-amino- and 7.beta.-amino-8-oxo-4-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acids are prepared. The acylated compounds are antibacterial agents.

REFERENCES:
cephalosporins and Penicillins, (Editor) Edwin H. Flynn, Academic Press, New York, (1972) p. 80.
Protective Groups in Organic Chemistry, (Ed.) J. F. W. McOmie, Plenum Press, New York, (1973) pp. 43-93 and pp. 183-215.

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