8-iso-prostaglandins for glaucoma therapy

Details 8-iso-prostaglandins for glaucoma therapy 8-iso-prostaglandins for glaucoma therapy

2007-05-01

2007-05-01

Fay, Zohreh (Department: 1618)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C514S573000, C514S913000

Reissue Patent

active

10073838

ABSTRACT:
The present invention relates to the use of 8-iso prostaglandins and their derivatives for decreasing intraocular pressure, for example in the treatment of glaucoma It is based, at least in part, on the discovery that 8-iso prostaglandin E2effectively decreased intraocular pressure by a trabecular meshwork outflow mechanism.

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Podos et al., Mar. 15, 1998, Invest. Ophtalmol. Visual Sci. 39(4): S258, abstract 1178-B57, 1998.
Wang et al., Mar. 15, 1997, Invest. Ophtalmol. Visual Sci. 38(4):S815, abstract 3795-B396.

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