8-iso- prostaglandins for glaucoma therapy

Details 8-iso- prostaglandins for glaucoma therapy 8-iso- prostaglandins for glaucoma therapy

1998-05-06

2000-03-14

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514573, 514913, A61K 31215, A61K 3119

Patent

active

060373687

ABSTRACT:
The present invention relates to the use of 8-iso prostaglandins and their derivatives for decreasing intraocular pressure, for example in the treatment of glaucoma It is based, at least in part, on the discovery that 8-iso prostaglandin E.sub.2 effectively decreased intraocular pressure by a trabecular meshwork outflow mechanism.

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patent: 5631287 (1997-05-01), Schneider
Podos et al., Mar. 15, 1998, Invest. Ophtalmol. Visual Sci. 39(4):S258, abstract 1178-B57 (title on the Internet several months earlier, believed to be in 1998).
Wang et al., Mar. 15, 1997, Invest. Ophtalmol. Visual Sci. 38(4):S815, abstract 3795-B396.

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