8-Halo-11,12-secoprostaglandins

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260398, 260404, 2604045, 2604109R, 260413, 260417, 260468D, 260535R, 424312, 424314, C11C 300

Patent

active

039910873

ABSTRACT:
This invention relates to 11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the treatment of hypertension, and for the prevention of thrombus formation.

REFERENCES:
patent: 3718667 (1973-02-01), Strike et al.
patent: 3759964 (1973-09-01), Siddall et al.
patent: 3857831 (1974-12-01), Hayashi et al.
patent: 3862972 (1975-01-01), Heslinga et al.
patent: 3882244 (1975-05-01), Lee
Merck Index (1968) pp. 878-879, "Prostaglandins".
Merck Index (1968) pp. 228, 432, Chaulmoogric Acid Esters.

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