8-glycine, des-19-leucine-calcitonin

Details 8-glycine, des-19-leucine-calcitonin 8-glycine, des-19-leucine-calcitonin

1986-05-05

1988-05-24

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Calcitonin; related peptides

C07K 736

Patent

active

047467282

ABSTRACT:
New peptides are disclosed which have biological activity of the same type as the known calcitonins and which have a glycine at position 8 instead of the natural valine found in that position. In addition these new peptides do not have a leucine in position 19. The position 19 leucine is omitted. Also resin peptides are disclosed which may be converted to peptides having such biological activity; and processes for producing said resin peptides and said calcitonin peptides.

REFERENCES:
patent: 4401593 (1983-08-01), Orlowski et al.
patent: 4497731 (1985-02-01), Orlowski et al.
patent: 4604238 (1986-08-01), Orlowski et al.
patent: 4639511 (1987-01-01), Orlowski et al.

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