8-fluoroimidazo 1,2-a pyridine derivatives as ligands for...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S300000, C544S294000, C546S121000

Reexamination Certificate

active

10515165

ABSTRACT:
A class of 8-fluoroimidazo[1,2-α]pyridine derivatives, substituted at the 3-position by an optionally substituted five-membered or six-membered heteroaromatic ring, being selective ligands for GABAAreceptors, in particular having high affinity for the α2 and/or α3 and/or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.

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patent: 7030128 (2006-04-01), Blackaby et al.
patent: 2005/0165048 (2005-07-01), Goodacre et al.
patent: WO01/38326 (2000-11-01), None
patent: WO01/90108 (2001-05-01), None
patent: WO02/076983 (2002-03-01), None
patent: WO03/076442 (2003-09-01), None
Clayton et al., CAS Document No. 139:261331, Registry No. 603272-68-0.
Kawamura et al., CAS Document No. 144:292780, Registry No. 878805-55-1.
Accession No. 2003:737761, Registry No. 603272-68-0.

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